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Eptifibatide

*This product has been discontinued!*
Eptifibatide is a cyclic heptapeptide containing six amino acids and one mercaptopropionyl (des-amino cysteinyl) residue. An interchain disulfide bridge is formed between the cysteine amide and the mercaptopropionyl moieties. Chemically it is N6 -(aminoiminomethyl)-N2 -(3-mercapto-1-oxopropyl-L- lysylglycyl-L-a-aspartyl- L-tryptophyl-L -prolyl-L-cysteinamide, cyclic (1Ø6)-disulfide. Eptifibatide binds to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibits platelet aggregation.
RP17308
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Description

Eptifibatide is a cyclic heptapeptide containing six amino acids and one mercaptopropionyl (des-amino cysteinyl) residue. An interchain disulfide bridge is formed between the cysteine amide and the mercaptopropionyl moieties. Chemically it is N6 -(aminoiminomethyl)-N2 -(3-mercapto-1-oxopropyl-L- lysylglycyl-L-a-aspartyl- L-tryptophyl-L -prolyl-L-cysteinamide, cyclic (1Ø6)-disulfide. Eptifibatide binds to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibits platelet aggregation.

Synonyms

Integrilin

Cas No 188627-80-7
Sequence
MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2
Molecular Formula C35H19N11O9S2
C Terminal NH2
Disulfide Bridge Mpa1-Cys7
Molecular Weight 831.96
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Purity > 95%
Format Bridge Map1-Cys7
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
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