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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » Protease-Activated Receptor-2 Activating Peptide

Protease-Activated Receptor-2 Activating Peptide

Synonyms PAR2-AP
Description A PAR-2 activating peptide (PAR-2-AP), the putative N-terminal activating peptide sequence of the rat PAR2 receptor (SLIGRL) is identical with the one previously cloned from murine tissue. We concluded that, like the thrombin receptor, the PAR2 receptor may play a pathophysiologic role in the regulation of vascular and gastric smooth muscle contractility.
Sequence
{Ser}{Leu}{Ile}{Gly}{Arg}{Leu}-NH2
Sequence Shortening SLIGRL-NH2
Molecular Formula C29H56N10O7
C Terminal NH2
Molecular Weight 656.83

Purity > 95%
Gmp Flag 0
Storage Store at -20°C.
Note


S. Post., et al. House dust mite‐induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production Allergy. 2013 Sep;68(9):1117-25.

Tasuku Akiyama., et al. Enhanced responses of lumbar superficial dorsal horn neurons to intradermal PAR-2 agonist but not histamine in a mouse hindpaw dry skin itch model. J Neurophysiol. 2011 Jun;105(6):281

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Cat. No. RP19975
Size
Price
1 mg $40.00