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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » PAR-1 agonist peptide

PAR-1 agonist peptide

Description This hexapeptide corresponding to residues 42-47 of the thrombin receptor has been shown to be a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 uM and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+.
Sequence Shortening SFLLRN
Molecular Formula C34H56N10O9
Molecular Weight 748.87

Purity 95%
Storage Store at -20°C.

Simmons Sarah., et al. Thrombin induces release of proinflammatory chemokines interleukin-8 and interferon-c-induced protein-10 from cultured human fetal astrocytes. Neuroreport. 2013 Jan;24(1):36-40.

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Cat. No. RP19979
1 mg $45.00