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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » β-amyloid (1-16)

β-amyloid (1-16)

Description Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Beta-amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer’s disease with Beta-amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage.
Sequence
{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}
{His}{His}{Gln}{Lys}
Sequence Shortening DAEFRHDSGYEVHHQK
Molecular Formula C84H119N27O28
Molecular Weight 1955.02

Purity 95%
Gmp Flag 0
Storage Store GenScript β-amyloid (1-16) at -20°C.
Note


Please add reference: Da Silva, GFZ. et al. J. Biol. Chem. 280, 16601 (2005)

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Cat. No. RP20103
Size
Price
0.5 mg $25.00