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Catalog Products » Other Products » Catalog Peptides » All Catalog Peptides » γ-2-MSH (41-58), amide

γ-2-MSH (41-58), amide

Description Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line.
Sequence
{Tyr}{Val}{Met}{Gly}{His}{Phe}{Arg}{Trp}{Asp}{Arg}{Phe}{Gly}
Sequence Shortening YVMGHFRWDRFG
Molecular Formula C74H99N21O16S
Molecular Weight 1570.78

Gmp Flag 0
Note




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Cat. No. RP20307
Size
Price
1 mg $46.00