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IKKγ NBD Inhibitory Peptide

*This product has been discontinued!*
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
RP20478
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Description

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
Synonyms

IKKγ NBD Inhibitory Peptide

Overview
Sequence
{Asp}{Arg}{Gln}{Ile}{Lys}{Ile}{Trp}{Phe}{Gln}{Asn}{Arg}{Arg}
{Met}{Lys}{Trp}{Lys}{Lys}{Thr}{Ala}{Leu}{Asp}{Trp}{Ser}{Trp}
{Leu}{Gln}{Thr}{Glu}
Sequence Shortening DRQIKIWFQNRRMKWKKTALDWSWLQTE
Molecular Formula C170H259N49O42S1
Molecular Weight 3693.3
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Properties
Purity > 95%
Storage Store the peptide at -20°C.
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