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PUMA BH3

*This product has been discontinued!*
This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
RP20510
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Description

This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Overview
Sequence
{Glu}{Glu}{Gln}{Trp}{Ala}{Arg}{Glu}{Ile}{Gly}{Ala}{Gln}{Leu}
{Arg}{Arg}{Met}{Ala}{Asp}{Asp}{Leu}{Asn}{Ala}{Gln}{Tyr}{Glu}
{Arg}
Sequence Shortening EEQWAREIGAQLRRMADDLNAQYER
Molecular Formula C128H202N42O43S1
Molecular Weight 3049.3
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Properties
Purity > 95%
Storage Store the peptide at -20°C.
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