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Orexin B, mouse/rat

Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control.
$200.00
RP30892-1

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Description

Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control.
Overview
Synonyms Orexin B, mouse/rat
Description Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control.
Sequence
{Arg}{Pro}{Gly}{Pro}{Pro}{Gly}{Leu}{Gln}{Gly}{Arg}{Leu}{Gln}
{Arg}{Leu}{Leu}{Gln}{Ala}{Asn}{Gly}{Asn}{His}{Ala}{Ala}{Gly}
{Ile}{Leu}{Thr}{Met}
Sequence Shortening RPGPPGLQGRLQRLLQANGNHAAGILTM
Molecular Formula C₁₂₆H₂₁₅N₄₅O₃₄S
C Terminal Amidation
Molecular Weight 2936.45
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Properties
Length 28
Purity >95%
Solubility Soluble in Ultrapure water under 1mg/ml
Form Lyophilized
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
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