> 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC
|Endotoxin Level||< 1 EU/μg of protein by LAL method|
|Biological Activity||The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be < 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg.|
|Expression System||E. coli|
|Theoretical Molecular Weight||15.3 kDa|
|N-terminal Sequence Analysis||The sequence of the first five N-terminal amino acids wa determined and found to be Met-Ala-Pro-Thr-Ser-Ser.|
|Apparent Molecular Weight||15,300 Da|
|Formulation||Lyophilized from a 0.2 μm filtered solution in 10 mM sodium citrate, pH 4.0.|
|Reconstitution||It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile 18 MΩ-cm H₂O up to 100 μg/ml.|
|Storage & Stability||Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.|
|Target Background||Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.|
|Synonyms||IL2; IL-2; TCGF; lymphokine; interleukin 2|
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
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