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Catalog Products » Recombinant Proteins » Catalog Proteins - View by Cat. No. » Betacellulin (BTC), Human

Betacellulin, Human

Synonyms Betacellulin ( BTC), Human;
Description Betacellulin (BTC) is a member of the EGF family of cytokines that also includes EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. At the amino acid sequence level, human mature BTC protein exhibits 80% identity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum.
Species Human
Source E. coli
Biological Activity The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2.0 x 107units/mg.
Sequence
DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK
QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY

Measured Molecular Weight Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
Purity >98% by SDS-PAGE and HPLC analyses.
Formulation Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
Endotoxin Level Less than 0.2EU/ug of rHuBetacellulin as determined by LAL method.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Usage This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Storage This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
Note ;


Cat. No.
Product Name
Price
Z03244-10
Betacellulin, Human - 10 ug
$59.00
Z03102-10
Betacellulin, Human - 10 ug
$59.00
Z03192-10
Betacellulin, Mouse - 10 ug
$49.00
Z03162-10
Betacellulin, Mouse(HEK 293-expressed) - 10 ug
$49.00
 



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Cat. No. Z02749
Size
Price
20 ug $159.00