Exodus-2/CCL21, Human

Exodus-2/CCL21 is a novel CC chemokine discovered independently by three groups from the EST database, and shows 21-33% identity to other CC chemokines. Exodus-2 contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxyl terminal domain. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis.

Price	$180.00
Cat. No.	Z02843-20
Size	20 μg 1 mg Buy in bulk
Quantity
Est. Delivery


Ask us a question

Product Introduction Background Bottom Notes

Product Introduction

Species

Human

Protein Construction

CCL21 (Ser24-Pro134)
Accession # O00585

Purity

> 97% as analyzed by SDS-PAGE
> 97% as analyzed by HPLC

Endotoxin Level

< 1 EU/μg of protein by LAL method

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10.0-100.0 ng/ml.

Expression System

E. coli

Theoretical Molecular Weight

12.2 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution in 20 mM PB, pH 7.4, 150 mM NaCl.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.

Storage & Stability

Upon receiving, this product remains stable for 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. Avoid repeated freeze-thaw cycles.

Back

Background

Target Background

Synonyms

6Ckine; CKb9; ECL; SCYA21; SLC; TCA4; C-C motif chemokine ligand 21

Back

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.