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Catalog Products » Recombinant Proteins » Cytokines » Interleukin-6 (IL-6), Rat (HEK 293-expressed)

Interleukin-6 (IL-6), Rat (HEK 293-expressed)



Synonyms 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Description Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
Accession No P20607.1
Species Rat
Source HEK 293
Specific Activity ED50 < 3 pg/ml, measured by a cell proliferation assay using 7TD1 Cells.
Sequence
FPTSQVRRGD FTEDTTHNRP VYTTSQVGGL ITYVLREILE
MRKELCNGNS DCMNSDDALS ENNLKLPEIQ RNDGCFQTGY
NQEICLLKIC SGLLEFRFYL EFVKNNLQDN KKDKARVIQS
NTETLVHIFK QEIKDSYKIV LPTPTSNALL MEKLESQKEW
LRTKTIQLIL KALEEFLKVT MRSTRQT

Measured Molecular Weight 21~26 kDa , observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4°C or up to 2 months at -20°C.




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Cat. No. Z03041
Size
Price
5 ug $65.00
25 ug $159.00
1 mg $2100.00
 
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