×
Catalog Products » Recombinant Proteins » Cytokines » TRAIL Receptor-2, Human

TRAIL Receptor-2, Human



Synonyms soluble TRAIL Receptor-2, DR5, TNFRSF10B, KILER, TRICK2A, TRICKB
Description TRAIL Receptor-2 is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling. The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells. TRAIL-R2 is associated with a decrease in the survival rates of breast cancer patients.
Accession No Q6FH58
Species Human
Source HEK 293
Specific Activity ED50 < 6 ng/ml, measured in a cell proliferation assay using RPMI-8226 cells in the presence of 25 ng/ml of human TRAIL.
Sequence
ALITQQDLAP QQRAAPQQKR SSPSEGLCPP GHHISEDGRD
CISCKYGQDY STHWNDLLFC LRCTRCDSGE VELSPCTTTR
NTVCQCEEGT FREEDSPEMC RKCRTGCPRG MVKVGDCTPW
SDIECVHKE

Measured Molecular Weight ~15 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Human TRAIL Receptor-2 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human TRAIL Receptor-2 should be stable up to 1 week at 4°C or up to 2 months at -20°C.




Notice there is no results found, you can visit "Citations Database" for other results.







For more documents, please visit "Technical Support".
Cat. No. Z03095
Size
Price
50 ug $85.00
10 ug $39.00
1 mg $569.00
 
*
*
*
*