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Catalog Products » Recombinant Proteins » Growth Factors » Granulocyte Colony-Stimulating Factor (G-CSF), Rat (HEK 293-expressed)

G-CSF, Rat (HEK 293-expressed)

Synonyms Granulocyte, Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFβ, pluripoietin
Description Among the family of colony-stimulating factors, Granulocyte Colony-Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation of leukemic myeloid cell lines into granulocytes and macrophages. G-CSF synthesis can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits G-CSF synthesis. In epithelial, endothelial, and fibroblastic cells, secretion of G-CSF is induced by Interleukin-17.
Accession No P97712
Species Rat
Source HEK 293
Biological Activity ED50 < 5 pg/ml, measured in a cell proliferation assay using NFS-60 cells.
Sequence
IPLLTVSSLP PSLPLPRSFL LKSLEQVRKI QARNTELLEQ
LCATYKLCHP EELVLFGHSL GIPKASLSSC SSQALQQTKC
LSQLHSGLFL YQGLLQALAG ISSELAPTLD MLHLDVDNFA
TTIWQQMESL GVAPTVQPTQ STMPIFTSAF QRRAGGVLVT
SYLQSFLETA HHALHHLPRP AQKHFPESLF ISI

Measured Molecular Weight 25~28 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Rat Granulocyte Colony-Stimulating Factor (G-CSF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Rat Granulocyte Colony-Stimulating Factor (G-CSF) should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03101
Size
Price
10 ug $85.00
50 ug $275.00
1 mg $2100.00