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Catalog Products » Recombinant Proteins » Neurotrophins » NGF Receptor, Human

NGF R, Human

Synonyms Gp80-LNGFR, p75 ICD, CD271, TNFRSF16
Description NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
Accession No P08138
Species Human
Source HEK 293
Biological Activity ED50 < 0.4 μg /ml, measured in a neutrolization assay using TF-1 cells in the presence of 10ng/ml human b-NGF.
Sequence
KEACPTGLYT HSGECCKACN LGEGVAQPCG ANQTVCEPCL
DSVTFSDVVS ATEPCKPCTE CVGLQSMSAP CVEADDAVCR
CAYGYYQDET TGRCEACRVC EAGSGLVFSC QDKQNTVCEE
CPDGTYSDEA NHVDPCLPCT VCEDTERQLR ECTRWADAEC
EEIPGRWITR STPPEGSDST APSTQEPEAP PEQDLIASTV
AGVVTTVMGS SQPVVTRGTT DN

Measured Molecular Weight 32-60 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human NGF Receptor remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03105
Size
Price
10 ug $49.00
50 ug $139.00
1 mg $1900.00