Synonyms | Growth Factor-9, GAF (Glia-activating factor), HBGF-9 |
Description | Fibroblast Growth Factor-9 (FGF-9), also known as Glia-activating factor (GAF) and HBGF-9, belongs to the heparin-binding growth factors family. It is a secreted protein that exists as monomer or homodimer. It interacts with FGFR-1, FGFR-2, FGFR-3, and FGFR-4 and plays an important role in regulating cell proliferation, differentiation and migration. It is reported that FGF-9 may be involved in glial cell growth and differentiation during development, gliosis during brain tissue regeneration, and glial tumor growth stimulation. Other reports indicate that FGF-9 plays a role in male development. |
Accession No | P31371 |
Species | Mouse |
Source | CHO |
Biological Activity | ED50 < 2ng/ml, measured in a cell proliferation assay using 3T3 cells. |
Sequence | LGEVGNYFGV QDAVPFGNVP VLPVDSPVLL SDHLGQSEAG GLPRGPAVTD LDHLKGILRR RQLYCRTGFH LEIFPNGTIQ GTRKDHSRFG ILEFISIAVG LVSIRGVDSG LYLGMNEKGE LYGSEKLTQE CVFREQFEEN WYNTYSSNLY KHVDTGRRYY VALNKDGTPR EGTRTKRHQK FTHFLPRPVD PDKVPELYKD ILSQS |
Measured Molecular Weight | ~28 kDa, observed by reducing SDS-PAGE. |
Purity | > 95% as analyzed by SDS-PAGE and HPLC. |
Formulation | Lyophilized after extensive dialysis against PBS. |
Reconstitution | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Endotoxin Level | < 0.2 EU/μg, determined by LAL method. |
Storage | Lyophilized recombinant Murine Fibroblast Growth Factor-9 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Murine Fibroblast Growth Factor-9should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Note | For research use only |
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