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Catalog Products » Recombinant Proteins » Growth Factors » Vascular Endothelial Growth Factor D (VEGF-D), Human

VEGF-D, Human

Synonyms Vascular Endothelial Growth Factor-D, FIGF
Description Vascular Endothelial Growth Factor (VEGF)-D, also known as c-Fos-induced growth factor (FIGF), is a member of the PDGF/VEGF growth factor family. It is expressed highly in lung, heart and small intestine, and at lower levels in skeletal muscle, colon and pancreas. It binds to VEGFR-2 and VEGFR-3 receptors and activates downstream signals. VEGF-D is a growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth. It is involved in many developmental and physiological processes including the formation of venous and lymphatic vascular systems during embryogenesis and the maintenance of differentiated lymphatic endothelium in adults. In tumor pathology, it has been reported to play a role in restructuring of lymphatic channels and regional lymph node metastasis.
Accession No O43915
Species Human
Source CHO
Biological Activity ED50 < 1 μg /ml, measured in a cell proliferation assay using HUVEC cells.
Sequence
FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST
NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI
SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR

Measured Molecular Weight 18-19 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Human VEGF-D remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human VEGF-D should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03125
Size
Price
10 ug $95.00
50 ug $275.00
1 mg $2100.00