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Catalog Products » Recombinant Proteins » Growth Factors » Granulocyte Colony-Stimulating Factor (G-CSF), Mouse

G-CSF, Mouse

Synonyms Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFb, pluripoietin
Description Granulocyte Colony-Stimulating Factor (G-CSF), also known as CSF-3 and MGI-1G, is a cytokine and hormone belonging to the IL-6 superfamily. It is expressed by monocytes, macrophages, endothelial cells, fibroblasts and bone marrow stroma. G-CSF stimulates the bone marrow to produce granulocytes and stem cells, and specifically stimulates the proliferation and differentiation of the neutrophilic granulocyte lineage. G-CSF has been used to stimulate white blood cell production after chemotherapy. It has also been used to boost the number of hematopoietic stem cells after bone marrow transplantation.
Accession No P09920
Species Mouse
Source CHO
Biological Activity ED50 <0.02ng/ml, measured in a cell proliferation assay using NFS-60 cells.
Sequence
VPLVTVSALP PSLPLPRSFL LKSLEQVRKI QASGSVLLEQ
LCATYKLCHP EELVLLGHSL GIPKASLSGC SSQALQQTQC
LSQLHSGLCL YQGLLQALSG ISPALAPTLD LLQLDVANFA
TTIWQQMENL GVAPTVQPTQ SAMPAFTSAF QRRAGGVLAI
SYLQGFLETA RLALHHLA

Measured Molecular Weight 22-24 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant murine G-CSF remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, murine G-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03163
Size
Price
10 ug $85.00
50 ug $275.00
1 mg $2100.00