Catalog Products »
Recombinant Proteins »
Other Catalog Proteins »
Keratinocyte Growth Factor (KGF/FGF-7), Human(CHO-expressed)
KGF/FGF-7, Human(CHO-expressed)
| Synonyms | Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 |
| Description | Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion. |
| Accession No | P21781 |
| Species | Human |
| Source | CHO |
| Biological Activity | ED50 < 1 ng /ml, measured in a proliferation assay using 4MBr5 cells. |
| Sequence | CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT |
| Measured Molecular Weight | 16-18 kDa, observed by reducing SDS-PAGE. |
| Purity | > 95% as analyzed by SDS-PAGE and HPLC. |
| Formulation | Lyophilized after extensive dialysis against PBS. |
| Reconstitution | Reconstituted in ddH2O or PBS at 100 μg/ml. |
| Endotoxin Level | < 0.2 EU/μg, determined by LAL method. |
| Storage | Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
| Note | For research use only |
For more documents, please visit "Technical Support".
| Cat. No. Z03174 | ||
|---|---|---|
| Size | Price | |
| 5 ug | $65.00 | |
| 25 ug | $159.00 | |
