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Catalog Products » Recombinant Proteins » Other Catalog Proteins » Keratinocyte Growth Factor (KGF/FGF-7), Human(CHO-expressed)

KGF/FGF-7, Human(CHO-expressed)

Synonyms Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
Description Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
Accession No P21781
Species Human
Source CHO
Biological Activity ED50 < 1 ng /ml, measured in a proliferation assay using 4MBr5 cells.
Sequence
CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC
RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK
GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY
ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM
AIT

Measured Molecular Weight 16-18 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03174
Size
Price
5 ug $65.00
25 ug $159.00