• English
  • Sign In
  • Contact Us
×
Catalog Products » Recombinant Proteins » Cytokines » Interleukin-6 (IL-6), His, Mouse

IL-6, His, Mouse

Synonyms 26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Description Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.
Accession No P08505
Species Mouse
Source CHO
Biological Activity ED50 < 3 pg /ml, measured in a bioassay using 7TD1 cells.
Sequence
FPTSQVRRGD FTEDTTPNRP VYTTSQVGGL ITHVLWEIVE
MRKELCNGNS DCMNNDDALA ENNLKLPEIQ RNDGCYQTGY
NQEICLLKIS SGLLEYHSYL EYMKNNLKDN KKDKARVLQR
DTETLIHIFN QEVKDLHKIV LPTPISNALL TDKLESQKEW
LRTKTIQFIL KSLEEFLKVT LRSTRQTHHH HHH

Measured Molecular Weight 24-26 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant murine Interleukin-6 (IL-6), His, Murine remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, murine Interleukin-6 (IL-6), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




Notice there is no results found, you can visit "Citations Database" for other results.







For more documents, please visit "Technical Support".

Cat. No. Z03189
Size
Price
5 ug $65.00
25 ug $159.00