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Catalog Products » Recombinant Proteins » Cytokines » Interleukin-13 (IL-13), His, Mouse(CHO-expressed)

IL-13, His, Mouse(CHO-expressed)

Synonyms NC300 (Human) P600 (Murine)
Description Interleukin-13 (IL-13), also known as T-cell activation protein P600, is an immunoregulatory cytokine belonging to the IL-4/IL-13 family. It is produced by activated Th2 cells, mast cells and NK cells. IL-13 signals through a receptor complex composed of IL-4Rα and IL13Rα1 (or IL13Rα2). IL-13 inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α and IL-6 by monocytes and macrophages. It also induces B cell activation and IgE secretion.
Accession No P20109
Species Mouse
Source CHO
Biological Activity ED50 < 20 ng /ml, measured in a cell proliferation assay using R&D TF-1 cells.
Sequence
PVPRSVSLPL TLKELIEELS NITQDQTPLC NGSMVWSVDL
AAGGFCVALD SLTNISNCNA IYRTQRILHG LCNRKAPTTV
SSLPDTKIEV AHFITKLLSY TKQLFRHGPF HHHHHH

Measured Molecular Weight 14-30 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant murine Interleukin-13 (IL-13), His remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, murine Interleukin-13 (IL-13), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03191
Size
Price
50 ug $275.00
10 ug $85.00
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