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Catalog Products » Recombinant Proteins » Growth Factors » Platelet-derived growth factor DD (PDGF-DD), Human

PDGF-DD, Human

Synonyms platelet-derived growth factor D, IEGF, SCDGFB
Description PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rβ homodimers and PDGF Rα/β heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Accession No Q9GZP0
Species Human
Source CHO
Biological Activity ED50 < 5 μg/ml, measured in a cell proliferation assay using 3T3 cells.
Sequence
SYHDRKSKVD LDRLNDDAKR YSCTPRNYSV NIREELKLAN
VVFFPRCLLV QRCGGNCGCG TVNWRSCTCN SGKTVKKYHE
VLQFEPGHIK RRGRAKTMAL VDIQLDHHER CDCICSSRPP
R

Measured Molecular Weight 19-21 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human PDGF-DD remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only


Cat. No.
Product Name
Price
Z03080-10
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$65.00
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PDGF-AA, Mouse - 1 mg
$1750.00
Z02892-10
PDGF-BB, Human - 10 ug
$159.00
Z03096-10
PDGF-BB, Mouse - 10 ug
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Z03179-10
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Cat. No. Z03195
Size
Price
10 ug $85.00
50 ug $195.00