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Catalog Products » Recombinant Proteins » Cytokines » Interleukin-3 (IL-3), His, Rat

IL-3, His, Rat

Synonyms MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
Description Interleukin-3 (IL-3), also known as MCGF, Multi-CSF, HCGF and P-cell stimulation factor, belongs tothe α-helixfamily of hematopoietic cytokines. It is produced by activated T-cells, mast cells and natural killer cells. IL-3 binds to the IL-3 receptor alpha subunit and recruits the signal-transducing common beta chain. IL-3induced signal transduction results in the survival, differentiation and proliferation of a variety of immune cells, such as macrophages, neutrophils, megakaryocytes, mast cells and hematopoietic stem cells. IL-3 often acts synergistically with other cytokines, such as IL-7, EPO, GM-CSF and IL-6, to exert its simulative function.
Accession No P04823
Species Rat
Source CHO
Biological Activity ED50 < 8 ng/ml, measured in a cell proliferation assay using NF S-60 cells.
Sequence
ISDRGSDAHH LLRTLDCRTI ALEILVKLPY PQVSGLNNSD
DKANLRNSTL RRVNLDEFLK SQEEFDSQDT TDIKSKLQKL
KCCIPAAASD SVLPGVYNKD LDDFKKKLRF YVIHLKDLQP
VSVSRPPQPT SSSDNFRPMT VECHHHHHH

Measured Molecular Weight 22-34 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant ratInterleukin-3 (IL-3), His remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rat Interleukin-3 (IL-3), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03196
Size
Price
50 ug $159.00
10 ug $85.00
1 mg $1200.00