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Catalog Products » Recombinant Proteins » Growth Factors » IGF-BP-2, His, Human

IGF-BP-2, His, Human

Synonyms Insulin-like growth factor-binding protein 2, IBP-2, BP-2
Description IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
Accession No P18065
Species Human
Source HEK 293
Biological Activity ED50 < 2 μg/ml, measured in a bioassay using FDC-P1 cells in the presence of 15 ng/ml human IGF-II.
Sequence
FRCPPCTPER LAACGPPPVA PPAAVAAVAG GARMPCAELV
REPGCGCCSV CARLEGEACG VYTPRCGQGL RCYPHPGSEL
PLQALVMGEG TCEKRRDAEY GASPEQVADN GDDHSEGGLV
ENHVDSTMNM LGGGGSAGRK PLKSGMKELA VFREKVTEQH
RQMGKGGKHH LGLEEPKKLR PPPARTPCQQ ELDQVLERIS
TMRLPDERGP LEHLYSLHIP NCDKHGLYNL KQCKMSLNGQ
RGECWCVNPN TGKLIQGAPT IRGDPECHLF YNEQQEARGV
HTQRMQHHHH HH

Measured Molecular Weight 6-20 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant human IGF-BP-2, Hisremains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, human IGF-BP-2, His should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only




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Cat. No. Z03201
Size
Price
10 ug $49.00
50 ug $225.00
1 mg $1900.00