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Catalog Products » Recombinant Proteins » Chemokines » LIX/CXCL5 (88aa), Rat

LIX/CXCL5 (88aa), Rat

Synonyms LIX, Epithelial Neutrophil Activating Peptide-78, CXCL5, ENA-78
Description LPSinduced CXC chemokine (LIX), also known as C-X-C motif chemokine 5(CXCL5), is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Rat LIX cDNA encodes a 130 aa residue precursor with a predicted 37 aa residue signal peptide and a 93 aa residue mature protein. Among human CXC chemokines, rat LIX is most closely related to human GCP-2 and ENA-78.LIX can signal through the CXCR2 receptor.
Recombinant rat LIX/CXCL5 (88aa) produced in CHO cells is a polypeptide chain containing 88 amino acids. A fully biologically active molecule, rrLIX/CXCL5 (88aa) has a molecular mass of 9.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Accession No P97885.1
Species Rat
Source CHO
Biological Activity The EC50 value of rat LIX/CXCL5 (88aa) on Ca2+ mobilization assay in CHO-K1/G15/rCXCR2 cells (human Ga15 and rat CXCR2 stably expressed in CHO-K1 cells) is less than 3 μg/ml.
Sequence
APFSAMVATE LRCVCLTLAP RINPKMIANL EVIPAGPHCP
KVEVIAKLKN QKDNVCLDPQ APLIKKVIQK ILGSENKKTK
RNALALVR

Measured Molecular Weight 9.6 kDa, observed by reducing SDS-PAGE.
Purity > 98% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Rat LIX/CXCL5(88aa) remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, rat LIX/CXCL5(88aa) should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note For research use only


Cat. No.
Product Name
Price
Z03250-10
LIX/CXCL5 (74aa), Mouse - 10 ug
$59.00
Z02851-20
LIX/CXCL5 (93aa), Mouse - 20 ug
$159.00
 



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Cat. No. Z03266
Size
Price
10 ug $55.00
50 ug $155.00
1 mg $1300.00