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Catalog Products » Recombinant Proteins » Other Catalog Proteins » UBE2C/UBCH10, Human

UBE2C/UBCH10, Human

Synonyms Human UBCH10; Human UBE2C; Ubiquitin-conjugating enzyme E2 C
Description Ubiquitin­conjugating Enzyme E2 C(UBE2C), known as Ubiquitin­conjugating Enzyme H10(UbcH10), is a 179 amino acid(aa) member of the yeast Ubc4/5 family of Ubiquitin­conjugating(E2) enzymes and has a predicted molecular weight of 19.5 kDa. UbcH10/UBE2C plays a critical role in the destruction of mitotic proteins which is essential for subsequent events in cell cycle progression. UbcH10/UBE2C recognizes TEK sequences in target proteins, mediates Lys11­linked ubiquitination, and helps promote targeted protein degradation.
Recombinant Human UBE2C produced in E. coli cells is a single non-glycosylated polypeptide chain containing 179 amino acids. A fully biologically active molecule, rhUBE2C has a molecular mass of 19.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Accession No O00762
Source E. coli
Biological Activity Not Available
Sequence
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM
TLMMSGDKGI SAFPESDNLF KWVGTIHGAA GTVYEDLRYK
LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE
KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT
AFKKYLQETY SKQVTSQEP

Measured Molecular Weight 19.5 kDa, observed by reducing SDS-PAGE
Purity > 95% as analyzed by SDS-PAGE&HPLC
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Human UBE2C remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human UBE2C should be stable up to 1 week at 4°C or up to 3 months at -20°C.
Note For research use only




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Cat. No. Z03334
Size
Price
10 ug $39.00
50 ug $69.00
1 mg $1050.00