• English
  • Sign In
  • Contact Us
×
Catalog Products » Recombinant Proteins » Growth Factors » Fibroblast Growth Factor-17 (FGF-17), Human

FGF-17, Human

Synonyms Fibroblast Growth Factor-17, FGFH
Description Fibroblast Growth Factor-17 (FGF-17) is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play multiple roles in biological functions, including angiogenesis, mitogenesis, cell differentiation and wound repair. FGF-17 plays an important role in organizing and inducing specific patterning at the midbrain/hindbrain junction. FGF-17 is also expressed in the hindgut, parts of thedeveloping skeleton, tail bud, major arteries, and heart. FGF-17 signals through hFGFR1c, 2c, 3c, and 4. FGF-17 signals induce patterning of the embryonic brain.
Recombinant Human FGF-17 produced in E .coli is a single non-glycosylated polypeptide chain containing 195 amino acids. A fully biologically active molecule rhFGF-17 has a molecular mass of 22.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Accession No O60258
Source E. coli
Biological Activity ED50 < 0.5 ng/mL, measured by the cell proliferation assay using Balb/c3T3 cells, corresponding to a specific activity of >2 × 106 units/mg.
Sequence
MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT
SGKHVQVTGR RISATAEDGNKFAKLIVETD TFGSRVRIKG AESEKYICMN
KRGKLIGKPS GKSKDCVFTE IVLENNYTAFQNARHEGWFM AFTRQGRPRQ
ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSAPTRRTKRTRR
PQPLT

Measured Molecular Weight 22.6 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Human Fibroblast Growth Factor-17 (FGF-17) remainsst able up to 6 months at lower than -70°C from date of receipt. Upon reconstitution Human FGF-17 should be stable up to 1 week at 4°C or up to 3 months at -20°C.
Note For research use only




Notice there is no results found, you can visit "Citations Database" for other results.







For more documents, please visit "Technical Support".

Cat. No. Z03339
Size
Price
10 ug $59.00
50 ug $159.00
1 mg $1350.00