Catalog Products » Growth Factors » TGF-β2, Mouse
Manual
Manual
COAs

TGF-β 2, Mouse

Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, hematopoietic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
$225.00
Z03432-10

Ask us a question
Product Introduction
Species Mouse
Protein Construction
TGF-β2 (Ala303-Ser414)
Accession # P27090
Purity ≥ 95% as analyzed by SDS-PAGE
Endotoxin Level < 1 EU/μg of protein by LAL method
Biological Activity Immobilized Recombinant Mouse TGFBR2 (C-Fc) at 5μg/ml (100 μl/well) can bind TGF-β 2, Mouse.
Expression System Human Cells
Apparent Molecular Weight ~12.7 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution in 4 mM HCl.
Reconstitution Dissolve the lyophilized protein in 4mM HCl. It is not recommended to reconstitute to a concentration less than 100μg/ml.
Storage & Stability Upon receiving, this product remains stable for 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. Avoid repeated freeze-thaw cycles.
Back

TGF-β 2, Mouse

»

TGF-β 2, Mouse

»

<
>

Background
Target Background Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, hematopoietic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Synonyms Transforming growth factor beta-2; TGFB2; Polyergin; G-TSF; Glioblastoma-derived T-cell suppressor factor; Cetermin; BSC-1 cell growth inhibitor; TGF-beta-2
Back

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.