Catalog Products » ACE-2, hFc, Human (CHO-expressed)
Manual
Manual
COAs

ACE-2 Fc Chimera, Human (CHO-expressed)

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase. ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE 2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. It has high binding affinity to S-RBD.
$380.00
Z03516-100

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Product Introduction
Species Human
Protein Construction
ACE-2 (Gln18-Ser740)
Accession # Q9BYF1		 hFc
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level < 1 EU/μg of protein by gel clotting method
Biological Activity ACE-2, hFc, Human (CHO-expressed) can bind with S-RBD in functional ELISA assay.
Expression System CHO
Theoretical Molecular Weight 110.5 kDa
Formulation Supplied as a solution in PBS pH 7.4.
Concentration Please refer to the COA for the specific lot.
Storage & Stability Upon receiving, this product remains stable for 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.
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ACE-2 Fc Chimera, Human (CHO-expressed)

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ACE-2 Fc Chimera, Human (CHO-expressed)

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ACE-2 Fc Chimera, Human (CHO-expressed)

Immobilized SARS-CoV-2 Spike protein (RBD, His Tag) (Cat. No. Z03483) at 1 μg/mL can bind ACE-2 Fc Chimera, Human (Cat. No. Z03516) with a serial dilution.
Mouse Anti-Human IgG Fc Antibody[HRP], mAb (Cat.No. A01854) is used as a secondary antibody (0.1 μg/mL). »

ACE-2 Fc Chimera, Human (CHO-expressed)

Lane 1: 1μg of ACE-2 Fc Chimera, Human (CHO-expressed), reducing(R)
> 95% as analyzed by SDS-PAGE »

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Background
Target Background Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase. ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE 2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. It has high binding affinity to S-RBD.
Synonyms Human Angiotensin-Converting Enzyme 2; ACE-2
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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


Citations
Kriangkrai Chawansuntati, et al. Safety and immunogenicity of CoronaVac and ChAdOx1 heterologous prime-boost vaccines in an overweight population in Chiang Mai, Thailand. Vaccine X. (2024-03)