CCL25, Mouse

CCL25 is a new member of the CC family chemokine. It is also called Thymus-expressed chemokine (TECK) because it is restricted produced by thymus and intestine. Especially, the dendritic cells derived from thymus but not bone marrow had been identified to be the source of CCL25. By binding with CCR9, it elicits its effects of chemotactic for thymocytes, macrophages, and dendritic cells. Additionally, CCL25 takes part in regulating the development of T-cells.

Price	$605.00
Cat. No.	Z03586-100
Size	100 μg 1 mg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Mouse

Protein Construction

CCL25 (Gln24-Asn144)
Accession # O35903

Purity

> 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC

Endotoxin Level

< 1 EU/μg of protein by LAL method

Biological Activity

The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-50.0 ng/ml.

Expression System

E. coli

Theoretical Molecular Weight

14.1 kDa

Formulation

Lyophilized from a 0.2 µm filtered solution in 20 mM PB, pH 7.4, 150 mM NaCl.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.

Storage & Stability

Upon receiving, this product remains stable for 6 months at -20°C or -70°C. Upon reconstitution, the product should be stable for 1 week at 2-8°C or for 3 months at -20°C. Avoid repeated freeze-thaw cycles.

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Background

Target Background

Synonyms

SCYA25; Ckb15

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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.