FGF-Basic, Porcine

Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine. FGF-basic is produced by fibroblasts, and vascular cells. It regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling.

Price	$106.00
Cat. No.	Z03822-100
Size	100 μg 1 mg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Porcine

Protein Construction

FGF-basic (Pro171-Ser316)
Accession # A0A287ADF0

Purity

≥ 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

ED₅₀ < 1.0 ng/ml, measured by a cell proliferation assay using BALB/3T3 cells, corresponding to a specific activity of > 1.0 ×10⁶ U/mg.

Expression System

E. coli

Theoretical Molecular Weight

16.4 kDa

Apparent Molecular Weight

20.1 kDa, on SDS-PAGE under reducing conditions

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4

Reconstitution

Before opening, centrifuge the vial briefly to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml

Storage & Stability

Upon receiving, this product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 1 week at 4℃ or for 3 months at -20℃ or below. Avoid repeated freeze-thaw cycles.

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The ED₅₀ as determined by a cell proliferation assay using BALB/3T3 cells is 0.1310 ng/ml »

Lane 1: 2 µg of FGF-basic，Porcine under reducing condition (R)

Lane 2: 2 µg of FGF-basic，Porcine non-reducing condition (NR) (N)

The purity is greater than 95% as analyzed by SDS-PAGE

Background

Target Background	Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine. FGF-basic is produced by fibroblasts, and vascular cells. It regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling.
Synonyms	Fibroblast Growth Factor-basic; FGF-2; BFGF; FGFB; HBGF-2; bFGF; Prostatropin

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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.