TROP-2/TACSTD2, His, Rat

Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.

Price	$185.00
Cat. No.	Z03844-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Rat

Protein Construction

TROP-2/TACSTD2 (Gln25-Gly270) Accession # Q6P9Z6	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

HEK293

Theoretical Molecular Weight

28.9 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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The purity of TROP-2/TACSTD2, His, Rat is greater than 95% as determined by SEC-HPLC. »

TROP-2/TACSTD2, His, Rat on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background	Trop-2 (Tumor-associated calcium signal transducer 2) is also known as epithelial glycoprotein-1 antigen (EGP-1). It is encoded by the TACSTD2 gene. The mutations of Trop-2 gene cause an autosomal recessive disorder. Trop-2 causes cancer cell growth, proliferation, invasion, migration, and survival of cancer cells
Synonyms	EGP1; EGP-1; TROP2; GA733-1; gp50; T16; TACSTD2; TROP-2; M1S1; TACD2

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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.