ROR1 hFc Chimera, Human/Cynomolgus/Rhesus macaque

ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.

Price	$180.00
Cat. No.	Z03932-100
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Product Introduction Background Bottom Notes

Product Introduction

Species

Human/Cynomolgus/Rhesus macaque

Protein Construction

ROR1 (Gln30-Glu403) Accession # Q01973-1	hFc
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

68.8 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4 .

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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The purity of ROR1 hFc Chimera, Human/Cynomolgus/Rhesus macaque ROR1 is greater than 95% as determined by SEC-HPLC. »

ROR1 hFc Chimera, Human/Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Immobilized ROR1 hFc Chimera, Human/Cynomolgus/Rhesus macaque at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-ROR1 Antibody, hFc Tag with the EC50 of 26.7 ng/ml determined by ELISA. »

Background

Synonyms

ROR1; NTRKR1; dJ537F10.1

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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.