CD117, His, Cynomolgus/Rhesus macaque

The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.

Price	$390.00
Cat. No.	Z04140-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Cynomolgus/Rhesus macaque

Protein Construction

CD117 (Gln26-Pro520) Accession # XP_005555332.1(Cynomolgus) / AFE78183.1(Rhesus macaque)	His
N-term	C-term

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

56.69 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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Immobilized CD117, His, Cynomolgus/Rhesus macaque, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CD117 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA. »

The purity of CD117, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC. »

CD117, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background	The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
Synonyms	SCFR; PBT; CD117; ckit; c-kit; KIT

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.