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FOLR2, His, Human

FOLR1 and FOLR2 are equipped with cellular glycosylphosphatidylinositol (GPI) anchors. FOLR1 is secreted from epithelia with or without a micelle-encapsulated GPI-anchor into milk and other body fluids/secretions, e.g. semen where its interaction with spermatozoa indicates a role in male fertility. FOLR1 and FOLR2 serve as serum biomarkers of various diseases. FOLR3 possesses no GPI-anchor and originates from secretory granules of neutrophil granulocytes; its concentration in serum correlates to the FOLR3 content in leukocytes and rises with increased leukocyte counts (infection, malignancy and pregnancy).
$190.00
Z05315-100

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Product Introduction
Species Human
Protein Construction
FOLR2 (Thr17-Met228)
Accession # P14207		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 25.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 30-38 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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FOLR2, His, Human

Immobilized FOLR2, His, Human, His Tag at 0.5 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-FOLR2 Antibody, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA. »

FOLR2, His, Human

The purity of FOLR2, His, Human is greater than 95% as determined by SEC-HPLC. »

FOLR2, His, Human

FOLR2, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background FOLR1 and FOLR2 are equipped with cellular glycosylphosphatidylinositol (GPI) anchors. FOLR1 is secreted from epithelia with or without a micelle-encapsulated GPI-anchor into milk and other body fluids/secretions, e.g. semen where its interaction with spermatozoa indicates a role in male fertility. FOLR1 and FOLR2 serve as serum biomarkers of various diseases. FOLR3 possesses no GPI-anchor and originates from secretory granules of neutrophil granulocytes; its concentration in serum correlates to the FOLR3 content in leukocytes and rises with increased leukocyte counts (infection, malignancy and pregnancy).
Synonyms FBP;FOLR2;OLR2;BETA-HFR;BETA HFR; FR-BETA;FR BETA; FR-P3; FR P3; β-HFR; β HFR; FR-β; FR β
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.