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Leptin hFc Chimera, Mouse

Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenital leptin deficiency (CLD) due to mutations in the leptin gene.
$340.00
Z06241-100

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Product Introduction
Species Mouse
Protein Construction
Leptin (Val22-Cys167)_x000D_
Accession # P41160		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 42.76 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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Leptin HFc Chimera, Mouse

The purity of Leptin hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC. »

Leptin HFc Chimera, Mouse

Leptin hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenital leptin deficiency (CLD) due to mutations in the leptin gene.
Synonyms Leptin; Obese protein; Obesity factor; LEP; OB; OBS; LEPD
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.