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PD-1/PDCD1 hFc Chimera, Mouse

Programmed cell death protein 1, also known as PD-1 and CD279, is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
$340.00
Z06299-100

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Product Introduction
Species Mouse
Protein Construction
PD-1/PDCD1 (Leu25-Gln167)_x000D_
Accession # NP_032824		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Mouse PD­L1, His Tag captured on CM5 Chip via anti­his antibody can bind PD-1/PDCD1 hFc Chimera, Mouse in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 42.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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PD-1/PDCD1 HFc Chimera, Mouse

The purity of PD-1/PDCD1 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC. »

PD-1/PDCD1 HFc Chimera, Mouse

PD-1/PDCD1 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

PD-1/PDCD1 HFc Chimera, Mouse

PD-1/PDCD1 hFc Chimera, Mouse, His Tag (Cat. PDL-MM110) captured on CM5 Chip via anti-his antibody can bind Mouse PD-1, hFc Tag with an affinity constant of 0.62 μM as determined in SPR assay (Biacore T200). »

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Background
Target Background Programmed cell death protein 1, also known as PD-1 and CD279, is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
Synonyms PDCD1; PD1; CD279; SLEB2; PD-1
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.