Catalog Products » Pentraxin 2/SAP hFc Chimera, Mouse
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Pentraxin 2/SAP hFc Chimera, Mouse

Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases.
$300.00
Z06304-100

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Product Introduction
Species Mouse
Protein Construction
Pentraxin 2/SAP (Gln21-Asp224)_x000D_
Accession # P12246		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 50.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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Pentraxin 2/SAP HFc Chimera, Mouse

The purity of Pentraxin 2/SAP hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC. »

Pentraxin 2/SAP HFc Chimera, Mouse

Pentraxin 2/SAP hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases.
Synonyms SAP; APCS; MGC88159; Pentraxin 2; PTX2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.