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TGF-alpha hFc Chimera, Mouse

Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic support for a role of TGFA arises from its presence at high levels in the epithelial tissue of the medial edge of the palatal shelves at the time of shelf fusion in mice.
$340.00
Z06369-100

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Product Introduction
Species Mouse
Protein Construction
hFc TGF-alpha (Val39-Ala88)_x000D_
Accession # P48030
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 32.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 38-42 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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TGF-alpha HFc Chimera, Mouse

The purity of TGF-alpha hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC. »

TGF-alpha HFc Chimera, Mouse

TGF-alpha hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic support for a role of TGFA arises from its presence at high levels in the epithelial tissue of the medial edge of the palatal shelves at the time of shelf fusion in mice.
Synonyms ETGF; TGF-alpha; TGF type 1; TGFA
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.