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PLAU/uPA, His, Rat

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
$390.00
Z06430-100

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Product Introduction
Species Rat
Protein Construction
PLAU/uPA (Gly20-Phe432)_x000D_
Accession # NP_037217.3		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Human uPAR, hFc Tag captured on CM5 Chip via Protein A can bind PLAU/uPA, His, Rat in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 46.91 kDa
Apparent Molecular Weight The protein migrates to 30-35 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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PLAU/uPA, His, Rat

The purity of PLAU/uPA, His, Rat is greater than 90% as determined by SEC-HPLC. »

PLAU/uPA, His, Rat

PLAU/uPA, His, Rat on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

PLAU/uPA, His, Rat

Human uPAR, hFc Tag captured on CM5 Chip via Protein A can bind PLAU/uPA, His, Rat, His Tag with an affinity constant of 4.31 μM as determined in SPR assay (Biacore T200). »

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Background
Target Background Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Synonyms PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.