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Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy
Authors: Jiexin Li, Ruiqi Yang, Chen Zhang, Jonathan F Lovell, Yumiao Zhang
Journal: J Am Chem Soc
PubMed ID: 40065259
Doi: 10.1021/jacs.4c18511
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Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers
Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li
Journal: Nature Communications
PubMed ID: 39952937
Doi: 10.1038/s41467-025-56407-7
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Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy
Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song
Journal: Adv Mater
PubMed ID: 39972681
Doi: 10.1002/adma.202411886
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Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy
Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang
Journal: Adv Mater
PubMed ID: 39955648
Doi: 10.1002/adma.202416574
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Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice
Authors: Yuxuan Chen , Xiaohong Chen , Yao Zhang , Meng Wang , Minqi Yang , Ruiji Wang , Xiaojie Yan , Shiyi Shao , Huhu Xin , Qida Hu , Wei Wei , Yuan Ping
Journal: Sci Transl Med
PubMed ID: 39813319
Doi: 10.1126/scitranslmed.adl5800
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Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence
Authors: Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li
Journal: Journal of nanobiotechnology
PubMed ID: 39844298
Doi: 10.1186/s12951-025-03103-9
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IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer
Authors: Masataka Amisaki, Abderezak Zebboudj, Hiroshi Yano, Siqi Linsey Zhang, George Payne, Adrienne Kaya Chandra, Rebecca Yu, Pablo Guasp, Zachary M. Sethna, Akihiro Ohmoto, Luis A. Rojas, Charlotte Cheng, Theresa Waters, Alexander Solovyov, Stephen Martis, Ashley S. Doane, Charlotte Reiche, Emmanuel M. Bruno, Martina Milighetti, Kevin Soares, Zagaa Odgerel, John Alec Moral, Julia N. Zhao, Mithat Gönen, …Vinod P. Balachandran
Journal: Nature
PubMed ID: 39814891
Doi: 10.1038/s41586-024-08426-5
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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine
Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo
Journal: Nature Communications
PubMed ID: 32710080
Doi: 10.1038/s41467-020-17504-x
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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine
Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo
Journal: Nature Communications
PubMed ID: 32710080
Doi: 10.1038/s41467-020-17504-x
Products & Services: Recombinant Proteins   
Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine
Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo
Journal: Nature Communications
PubMed ID: 32710080
Doi: 10.1038/s41467-020-17504-x
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