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Loss-of-function KCa2.2 mutations abolish channel activity
Authors: Young-Woo Nam , Mohammad Asikur Rahman , Grace Yang , Razan Orfali , Meng Cui , Miao Zhang
Journal: Am J Physiol Cell Physiol
PubMed ID: 36717104
Doi: 10.1152/ajpcell.00584.2022
Products & Services: PCR Cloning and Subcloning   
S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme-substrate interaction
Authors: Liam Butler , Carolina Locatelli , Despoina Allagioti , Irina Lousa , Kimon Lemonidis , Nicholas C O Tomkinson , Christine Salaun , Luke H Chamberlain
Journal: J Biol Chem
PubMed ID: 36442513
Doi: 10.1016/j.jbc.2022.102754
Spike-mediated viral membrane fusion is inhibited by a specific anti-IFITM2 monoclonal antibody
Authors: Anna Basile , Carla Zannella , Margot De Marco , Giuseppina Sanna , Gianluigi Franci , Massimiliano Galdiero , Aldo Manzin , Vincenzo De Laurenzi , Massimiliano Chetta , Alessandra Rosati , Maria Caterina Turco , Liberato Marzullo
Journal: Antiviral Res
PubMed ID: 36669656
Products & Services: Monoclonal Antibody Services   
Structure of monkeypox virus DNA polymerase holoenzyme
Authors: Qi Peng, Yufeng Xie, Lu Kuai, Han Wang, Jianxun Qi, George F Gao, Yi Shi
Journal: Science (New York, N. Y.)
PubMed ID: 36520947
Doi: 10.1126/science.ade6360
Products & Services: Gene Synthesis   
Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47
Authors: Huanhuan Hu, Rongjie Cheng, Yanbo Wang, Xiaojun Wang, Jianzhuang Wu, Yan Kong, Shoubin Zhan, Zhen Zhou, Hongyu Zhu, Ranran Yu, Gaoli Liang, Qingyan Wang, Xiaoju Zhu, Chen-Yu Zhang, Rong Yin, Chao Yan , Xi Chen
Journal: The Journal of Clinical Investigation
PubMed ID: 36413402
Doi: 10.1172/JCI153470
Products & Services: Mutant Libraries   
Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
Authors: Alhaji H. Janneh, Mohamed Faisal Kassir, F. Cansu Atilgan, Stephen Tomlinson, Shikhar Mehrotra, Besim Ogretmen
Journal: Cell Reports
Products & Services: Catalog Antibody   Plasmid DNA Preparation   
Structure-activity relationship studies for inhibitors for vancomycin-resistant and human carbonic anhydrases
Authors: Weiwei An, Katrina J Holly, Alessio Nocentini, Ryan D Imhoff, Chad S Hewitt, Nader S Abutaleb, Xufeng Cao, Mohamed N Seleem, Claudiu T Supuran, Daniel P Flaherty
Journal: J Enzyme Inhib Med Chem
PubMed ID: 35758212
Doi: 10.1080/14756366.2022.2092729
Products & Services: Plasmid DNA Preparation   
Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A
Authors: Dell'Orco D, Dal Cortivo G.
Journal: Sci Rep
PubMed ID: 31882816
Doi: 10.1038/s41598-019-56606-5
Products & Services: Gene Synthesis   
SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate
Authors: Alexander J Garvin , Alexander J Lanz , Joanna R Morris
Journal: Sci Rep
PubMed ID: 36494414
Doi: 10.1038/s41598-022-25665-6
Products & Services: Peptide Synthesis   
Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promote antiinflammatory polarization of macrophage and bone repair via MAPK/JNK inhibition and OXPHOS activation
Authors: Hao Wu, Dong Hui, Zhen Tang, Yu Chen, Yichao Liu, Mo Wang, Xinghui Wei, Ning Wang, Shusen Bao, Dongmei Yu, Zhigang Wu, Zhenda Yang, Xiaokang Li, Zheng Guo, Lei Shi
Journal: Biomaterials
Doi: 10.1016/j.biomaterials.2022.121990
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