Codon optimization: Why & how to design DNA sequences for optimal soluble protein expression

Have you struggled with low protein expression levels in your experiments? This webinar will explain the principles of codon optimization and explore case studies showing how it improves protein expression up to 100-fold. Research has revealed dozens of DNA sequence features that influence the efficiency of each step required to achieve soluble target protein expression. We will review the critical publications that inform GenScript's patented algorithm and the data showing how our algorithm compares to our competitors. We will look at peer-reviewed papers that employed codon-optimized synthetic genes for heterologous protein expression in different host systems, including bacteria, yeast, plant, and human cells. Finally, we will see how GenScript's codon optimization can provide clever solutions to molecular biology problems in specialized applications.

Speaker-related Webinars

Identify the optimal protein purification strategy for your recombinant protein production

Are you challenged with obtaining sufficient amount of high purity proteins for your applications? Almost unavoidably, every protein purification step results in some degree of protein loss.

Learn More

Recombinant protein expression & purification

Are you struggling with the amount and/or purity of your recombinant protein? Attend this online seminar for solutions to the challenges in recombinant protein expression & purification.

Learn More

Accelerating Lead Identification Through Paramagnetic Bead Purification Technology

High throughput purification is a critical step in antibody engineering and lead identification. Paramagnetic bead technology allows a single step purification of targets by simply adding the beads directly

Learn More

Efficient stable cell pool/cell line development for large-scale antibody and protein production

Interested in rapid and efficient stable cell pool/cell line development for large-scale production of your recombinant antibodies and proteins? If so, this webinar may be for you.

Learn More

Chaperone co expression strategies for recombinant soluble protein production in E. Coli

Recombinant protein expression in E. coli often results in the formation of insoluble aggregates called inclusion bodies.

Learn More