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Webinars » Anti-idiotype Antibody: Generation and application in therapeutic antibody development

Anti-idiotype Antibody: Generation and application in therapeutic antibody development

Anti-idiotype antibodies (anti-IDs) recognize the idiotype; paratope binding region, of another antibody, usually an antibody drug. This makes them incredibly useful in pharmacokinetic (PK) and pharmacodynamic (PD) studies to specifically measure circulating antibody drug concentrations during pre-clinical and clinical studies. In addition, the resemblance of anti-IDs to anti-drug antibodies(ADAs) makes them perfect positive control or reference standards in immunogenicity assays.

In this webinar, we will cover:

  • A general introduction to anti-IDs, including an overview of the different types of anti-IDs and their corresponding applications.
  • The general strategies of raising anti-IDs,focusing on the decision making process of clone selection.
  • We will review some common technical challenges which come with anti-IDs generation and our recommended solutions for them.
Dr. chenli

Speaker: Dr. Li Chen is the Principal Project Manager of GenScript’s Project Management Center, and is also in charge of the therapeutic antibody discovery service platform at GenScript USA Inc. Dr. Chen received his Ph.D. from the University of Massachusetts Medical School, specializing in immunology and bioinformatics. Dr. Chen has extensive experience in Antibody drug discovery, including publication of three patents in antibody discovery field.

Date & Time: October 18, 2018; 8:00-9:00 A.M. GMT

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