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Applications & Industries

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Gene And Cell Engineering Research

As recent developments in gene and cell editing continues to advance medicine and drug discovery, the demand for highly customizable, quality assured, full-service providers have mounted. GenScript is proud to work alongside scientists worldwide to bring these tailor-made solutions to you. With our proven track record, experienced scientists and project management teams and extensive portfolios, GenScript promises top notch services for the most urgent medical and scientific breakthrough.

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Gene Engineering

Gene engineering works by altering the patients’ genetic material to treat or cure the disease

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Cell Engineering

Cell engineering aims to treat or prevent diseases by selecting, manipulating, propagating and ultimately reintroducing cells back into the patient’s body.

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Target Identification
Lead Validation
Pre-clinical Studies
Target Identification
Lead Validation
Pre-clinical Studies

High-throughput Screens

Functional Assays

Gene Delivery

Animal and Cell Engineering

Gene Delivery

Scale up

CAR and Antibody Discovery

Immune Cell Profiling

CAR and Antibody Optimization

Animal and Cell Engineering

High-throughput Screens:
Automated evaluation of large libraries against selected and specific targets to understand their effect on the biological system of interest and accelerate drug discovery.

Functional Assays:
Systematic experiments designed to quantify and qualify the role of molecules of interest in a pathway or biological process.

Gene Delivery:
Introduction of genetic material of interest through different methods and approaches into targeted cells for integration into the host genome.

Animal and Cell Engineering:
Genetic modification of animals and cells to develop in vivo and in vitro research models.

Gene Delivery:
Introduction of genetic material of interest through different methods and approaches into targeted cells for integration into the host genome.

Scale up:
Increasing batch size to meet commercial requirements through process engineering, production optimization and quality control and assurance practices.

CAR and Antibody Discovery:
Identification of epitopes and sequences targeting specific antigens to cause disease modulating effects.

Immune Cell Profiling:
Systematic characterization of molecular markers in immune cells involved in a particular pathway or biological process.

CAR and Antibody Optimization:
Optimization of epitopes and sequences targeting specific antigens to cause disease modulating effects.

Animal and Cell Engineering:
Designing and developing animal and cellular models to perform in vivo assays for research.

Dr. Maung Nyan Win
Sr. Application Scientist GenScript

Tailor-made mutant libraries for precision engineering

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Shondra M. Pruett-Miller, PhD
Director, St. Jude Children’s Research Hospital Comprehensive Cancer Center

CRISPR in Creating Knockin Cell Lines and Animal Models - Functionalizing Genome Editing for a Broad Range of Targets

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James Chon, Ph.D
Field Application Scientist Genscript USA Inc.

Effective gene editing using the CRISPR RNP system:higher editing efficiency, lower off-target effects, and minimal cytotoxicity

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Josh Wang, Ph.D.
R&D Sr. Scientist Genscript USA Inc.

Unleash the power of NGS target enrichment by semiconductor

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Yifan Li
Senior scientist at GenScript USA Inc

Building DNA Libraries to Explore the Combinatorial Design Space

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Niren Murthy, PhD
Professor, Department of Bioengineering UC Berkeley- innovative Genomics Institute

Therapeutic Gene Editing Enabled by New Delivery Vehicles

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Killian S. Hanlon, PhD
Research Fellow, Harvard Medical School, Massachusetts General Hospital

Library-selected AAV variants can effectively translate to non-human primates in the spinal cord and cochlea

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Casey Maguire, PhD
Associate Professor of Neurology, Harvard Medical School and Investigator, Massachusetts General Hospital

Solutions for in vivo barriers to gene therapy vectors

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Ye Liu, PhD
Senior Director of Gene Transfer Technologies, REGENXBIO Inc.

Discovering the Next Generation AAV Vector Through Capsid Engineering and Expression Cassette Optimization

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James Chon, Ph.D
Field Application Scientist Genscript USA Inc.

Effective gene editing using the CRISPR RNP system:higher editing efficiency, lower off-target effects, and minimal cytotoxicity

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Lumeng Ye, Ph.D.
Sr. Scientist, GenScript USA Inc.

Precise and Efficient Non-viral CRISPR Gene Editing Solutions

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Coming Soon

Dr. Stephen Hughes
Director of New Platform Development, GenScript

Pre-clinical AAV production and optimization: Not as easy as it looks!

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Rama Shivakumar
Manager, Technical Applications at MaxCyte Inc.

Clinical Scale Gene Editing for Cell and Gene Therapy Applications

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Alexander Marson, MD, PhD
Director, Gladstone-UCSF Institute of Genomic Immunology

Reprogramming Human T Cells with CRISPR

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Gal Cafri, PhD
Immunotherapy and Genetic Engineering Group Leader, Sheba Medical Center

Genetic engineering approaches to support clinical applications of T-cell receptor libraries targeting oncogenic mutations

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Anna Pasetto, PhD, Assistant Professor
Managing director of pre-GMP facility
Department of Laboratory Medicine, Karolinska Institutet

TCR targets validation through T cell activation

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Joshua Burgess, PhD
Advance Queensland Early Career Research Fellow of Translational Research Institute, Queensland University of Technology

Identification and Characterization of a Novel Biomarker for Cancer Therapy

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J Joseph Melenhorst, PhD
Professor, Pathology and Laboratory Medicine, University of Pennsylvania and Director, Biomarker Program, Parker Institute for Cancer Immunotherapy, UPenn

Response to Second Generation CAR T Cell Therapy: It takes (at least) Two to Tango

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Ramarao Vepachedu, PhD
Development Scientist IV, Leidos Biomedical Research, Inc

CRISPR/Cas9-based genome editing for autologous CAR-T cell production

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Matthew Porteus, MD, PhD
Professor, Stanford University, School of Medicine

Targeted Integration in Stem Cells

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Shondra M. Pruett-Miller, PhD
Director, St. Jude Children's Research Hospital Comprehensive Cancer Center

Operationalizing Genome Editing Across a Broad Range of Genomic and Cellular Targets

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