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Catalog Products » Other Products » Stable Cell Lines » Human Recombinant V2 Vasopressin Receptor Stable Cell Line

CHO-K1/V2/Gα15 Stable Cell Line


Synonyms Human Recombinant V2 Vasopressin Receptor Stable Cell Line
Description Arginine vasopressin (AVP) is a cyclic nonapeptide that acts by binding to a family of vasopressin receptors that includes V1a, V1b, and V2 receptors. In particular, V2 receptors are expressed in kidney where vasopressin exerts its antidiuretic action. V1a and V1b couple to Gq and calcium release, whereas V2 couples to Gs. Mutations in V2 result in X-linked nephrogenic diabetes insipidus, a syndrome in which the kidney is unable to concentrate urine, leading to dehydration and hypernatremia. Conversely, elevated levels of AVP lead to hyponatremia in the syndrome of inappropriate antidiuretic hormone secretion (SIADH), congestive heart failure or cirrhosis, and V2 selective antagonists have been developed to treat these conditions.
Species Human
Culture Medium Ham's F12, 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/V2/Gα15 Stable Cell Line
CHO-K1/V2/Gα15 Stable Cell Line


Cat. No.
Product Name
Size
Price
Quantity
RP20275 [Arg8]-Vasopressin (AVP)
1 mg
$42.00
 


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Cat. No. M00170
Size
Price
2 vials $8500.00
24 hour
 
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