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Catalog Products » Other Products » Stable Cell Lines » Human Recombinant NK1 Tachykinin Receptor Stable Cell Line

CHO-K1/NK1 Stable Cell Line


Synonyms Human Recombinant NK1 Tachykinin Receptor Stable Cell Line
Description Tachykinins are peptides sharing the common C-terminal amino acid sequence Phe-X-Gly-Leu-Met-NH2. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and peripheral nervous systems. It plays a role as both a neurotransmitter and a neuromodulator. Their actions are mediated by binding with three distinct receptors, namely, NK1, NK2, and NK3. NK1 has high affinity with substance P. In the CNS, NK1 has been implicated to play a role in regulating neuronal survival and degeneration. In the cardiovascular system, NK1 mediates endothelium-dependent vasodilatation and plasma protein extravasations. In the gastrointestinal system, NK1 receptors mediate intestinal motility, secretion, and vascular functions. SP-NK1 receptor communication is also involved in glioma development and progression. NK1 receptor antagonists may have several therapeutic applications in diseases mediated by tachykinins, such as pulmonary disorders, gut disorders, and the pathophysiology of depression.
Species Human
Culture Medium Ham's F12, 10% FBS, 400 μg/ml G418
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/NK1 Stable Cell Line
CHO-K1/NK1 Stable Cell Line


Cat. No.
Product Name
Size
Price
Quantity
RP10178 Substance P
5 mg
$43.00
RP10207 [Nle11]-Substance P
1 mg
$24.00
RP10210 [Sar9]-Substance P
1 mg
$33.00
 


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Cat. No. M00199
Size
Price
2 vials $8500.00
24 hour
 
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