×
Catalog Products » Other Products » Stable Cell Lines » Human Recombinant PAR4 Proteinase-activated Receptor Stable Cell Line

CHO-K1/PAR4 Stable Cell Line


Synonyms Human Recombinant PAR4 Proteinase-activated Receptor Stable Cell Line
Description Protease-activated receptor (PAR)-4 is a member of a unique family of GPCRs. The protease-activated receptors (PARs) that are activated by proteolytic cleavage of the N-terminal domain of the receptor reveal a tethered ligand. The PAR family consists of 4 receptors; PAR1 and PAR3 are activated by thrombin, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al., 2001). PAR4 is a recently identified low-affinity thrombin receptor that plays a pathophysiological role in many types of tissues including the lung. Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, indicating that PAR4 is a potential target for treatment of thrombosis in humans.
Species Human
Culture Medium Ham's F12, 10% FBS, 400 μg/ml G418
Freeze Medium 45% Ham's F12, 45% FBS, and 10% DMSO

Storage Liquid nitrogen immediately upon delivery

CHO-K1/PAR4 Stable Cell Line
CHO-K1/PAR4 Stable Cell Line




Notice there is no results found, you can visit "Citations Database" for other results.






For more documents, please visit "Technical Support".
Cat. No. M00206
Size
Price
2 vials $8500.00
24 hour
 
*
*
*
*