|Synonyms||A1 receptor, Ri, RDC7, adenosine A1 receptor , A1AR, A1R, A1-AR, AA1R, Ri|
|Description||ADORA1 is a receptor for adenosine. It is demonstrated that the ADORA1 receptor is ubiquitous throughout the entire body. Activation of ADORA1 elicits an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration. ADORA1 receptors are implicated in sleep promotion by inhibiting wake promoting cholinergic neurons in the basal forebrain. Adenosine antagonists are widely used in neonatal medicine.|
|Culture Medium||DMEM, 10% FBS, 100 μg/ml Hygromycin B, 200 μg/ml Zeocin|
|Freeze Medium||45% culture medium, 45% FBS, 10% DMSO|
|Storage||Liquid nitrogen immediately upon delivery|
|Functional assay for ADORA1 receptor
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