The P2Y receptor 12 (P2Y12) is a Gi-coupled GPCR expressed in platelets, brain tissues, vascular smooth muscle cells. P2Y12 can sustain platelet aggregation and promote thrombus growth and stabilization. It also plays a function in dense and alpha granule secretion, p-selectin expression and microparticle formation.
P2Y12 receptor , P2T, P2YAC, P2TAC, P2Y?, P2Ycyc, SP1999, P2YADP, P2T, P2Y12, HORK3, P2Y purinoceptor 12, P2Y12 platelet ADP receptor, purinergic receptor P2Y, G-protein coupled 12, 2900079B22Rik, 4921504D23Rik
|Freeze Medium||45% culture medium, 45% FBS, 10% DMSO|
|Culture Medium||DMEM, 10% FBS, 50 μg/ml Hygromycin B, 200 μg/ml Zeocin|
|Storage||Liquid nitrogen immediately upon delivery|
|Functional assay for P2Y12 receptor|
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